![]() The signs and symptoms of the disorder result from deterioration of cells in areas of your brain, especially those that help you control body movements and thinking. The cause of progressive supranuclear palsy isn't known. Request an Appointment at Mayo Clinic Causes Make an appointment with your doctor if you experience any of the signs and symptoms listed above. A surprised or frightened facial expression, resulting from rigid facial muscles.Difficulties with reasoning, problem-solving and decision-making.Impulsive behavior, or laughing or crying for no reason.Loss of interest in pleasurable activities.Problems with swallowing, which may cause gagging or choking.Stiffness (especially of the neck) and awkward movements.They generally get worse over time and may include: This difficulty with focusing the eyes can make some people spill food or appear disinterested in conversation because of poor eye contact.Īdditional signs and symptoms of progressive supranuclear palsy vary and may mimic those of Parkinson's disease and dementia. You may not be able to look downward, or experience blurring and double vision. ![]() An inability to aim your eyes properly.A tendency to fall backward can occur very early in the disease. The characteristic signs and symptoms of progressive supranuclear palsy include:
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